CDKN2B, cyclin dependent kinase inhibitor 2B, 1030

N. diseases: 440; N. variants: 13
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.020 GeneticVariation disease BEFREE In the cross-trait meta-analyses, we identified (1) 14 genetic loci (including NEGR1, CADM2, PMAIP1, PARK2) that are associated with both obesity and SSRIs treatment response; (2) five genetic loci (LINC01412, PHACTR1, CDKN2B, ATXN2, KCNE2) with effects on CAD and SSRIs treatment response. 30610379 2019
CUI: C0028754
Disease: Obesity
Obesity 		0.020 AlteredExpression disease BEFREE CDKN2B expression was regulated by obesity status, and this effect was stronger in carriers of 9p21 risk alleles. 24680834 2014