CCNO, cyclin O, 10309

N. diseases: 67; N. variants: 11
Disease: Lung diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.020 Biomarker group BEFREE In PCD, there was significant heterogeneity of lung disease, patients who had pathogenic variants in CCNO presented earlier, and those with CCDC40 and CCNO had worse lung disease, and poorer nutritional status compared with the other subgroups. 31765523 2020
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.020 GeneticVariation group BEFREE Using a whole-exome sequencing strategy, we identified recessive CCNO (encoding cyclin O) mutations in 16 individuals suffering from chronic destructive lung disease due to insufficient airway clearance. 24747639 2014