Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine
0.020 GeneticVariation disease BEFREE Alcohol consumption, alcohol dehydrogenase 3 polymorphism, and colorectal adenomas. 12750236 2003
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine
0.020 GeneticVariation disease BEFREE We examined folate and alcohol intake and genetic polymorphisms in methylenetetrahydrofolate reductase [MTHFR 667-->T (ala-->val) and MTHFR 1298A-->C (gln-->ala)] (associated with reduced MTHFR activity) and in alcohol dehydrogenase 3 [ADH3 (2-2) associated with decreased alcohol catabolism] in relation to risk of colorectal adenoma in the Health Professionals Follow-Up Study. 14578131 2003