Disease: Impaired cognition ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.040 GeneticVariation disease BEFREE Our findings imply that ABCA7 rs3764650 risk genotype may diminish the neuroprotective effects of aerobic fitness, and, they suggest differing risk patterns between cognitive decline and fitness by ABCA7 genotype. 31024289 2019
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.040 GeneticVariation disease BEFREE We identified significant aggregate-level associations between cognitive decline and the gene regions BIN1, CD33, CELF1, CR1, HLA cluster, and MEF2C in the all-female cohort and significant associations with ABCA7, HLA cluster, MS4A6E, PICALM, PTK2B, SLC24A4, and SORL1 in the all-male cohort. 27005436 2016
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.040 Biomarker disease BEFREE Our results suggest that CR1, ABCA7, and APOE correlate with specific aspects of cognitive impairments in AD patients. 24530172 2014
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.040 AlteredExpression disease BEFREE We found that ABCA7, CD33, and CR1 expression levels were associated with clinical dementia rating (CDR), with higher expression being associated with more advanced cognitive decline. 23226438 2012