KLF2, Kruppel like factor 2, 10365

N. diseases: 132; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.350 Biomarker disease CTD_human Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.350 AlteredExpression disease BEFREE A Novel lncRNA, LINC00460, Affects Cell Proliferation and Apoptosis by Regulating KLF2 and CUL4A Expression in Colorectal Cancer. 30092404 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.350 Biomarker disease BEFREE Rescue assays were used to determine whether P57 and Kruppel-like factor 2 (KLF2) were involved in SH3PXD2A-ASl-dependent CRC proliferation. 29734178 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.350 Biomarker disease BEFREE Collectively, we demonstrated that KLF2 mediates CRC cell biological processes including cell growth and apoptosis via regulating the HIF-1α/Notch-1 signal pathway. 28628187 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.350 AlteredExpression disease BEFREE Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancer. 28112720 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.350 AlteredExpression disease BEFREE A novel lncRNA, LL22NC03-N64E9.1, represses KLF2 transcription through binding with EZH2 in colorectal cancer. 28938648 2017