Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519680
Disease: Tumor Immunity
Tumor Immunity
0.030 Biomarker phenotype BEFREE In the course of modeling the naturally occurring tumor immunity seen in patients with paraneoplastic cerebellar degeneration (PCD), we discovered an unexpectedly high threshold for breaking CD8+ cytotoxic T cell (CTL) tolerance to the PCD autoantigen, CDR2. 29093272 2017
CUI: C1519680
Disease: Tumor Immunity
Tumor Immunity
0.030 AlteredExpression phenotype BEFREE Neoplastic expression of Cdr2 in ovary and breast tumors triggers an autoimmune response that suppresses tumor growth by developing tumor immunity, but culminates in cerebellar degeneration when Cdr2-specific immune cells recognize neuronal Cdr2. 19581925 2009
CUI: C1519680
Disease: Tumor Immunity
Tumor Immunity
0.030 Biomarker phenotype BEFREE This leads to an immune response to cdr2 that is associated with tumor immunity and autoimmune cerebellar degeneration. 10465786 1999