DLC1, DLC1 Rho GTPase activating protein, 10395

N. diseases: 144; N. variants: 21
Disease: Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.040 AlteredExpression group BEFREE Aberrant gene promoter methylation of p16, FHIT, CRBP1, WWOX, and DLC-1 in Epstein-Barr virus-associated gastric carcinomas. 25720522 2015
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.040 PosttranslationalModification group BEFREE Recently, we and others identified DLC1 (ARHGAP7) as a functional TSG frequently methylated in multiple carcinomas. 17965626 2008
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.040 AlteredExpression group BEFREE Expression of the tumor suppressor deleted in liver cancer-1 (DLC-1) is lost in non-small cell lung (NSCLC) and other human carcinomas, and ectopic DLC-1 expression dramatically reduces proliferation and tumorigenicity. 17932950 2008
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.040 Biomarker group BEFREE DLC-1 protein was not detected in 8 of 27 (30%) prostate carcinomas and 11 of 21 (52%) benign prostatic hyperplasias. 16533763 2006