NDRG1, N-myc downstream regulated 1, 10397

N. diseases: 225; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 AlteredExpression disease BEFREE For both adenocarcinoma (p = 0.031) and squamous cell carcinoma (p=0.034), the survival curve of patients negative for nuclear NDRG1/Cap43 expression differed significantly from that of patients who were positive. 22481237 2012
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 AlteredExpression disease BEFREE Lung adenocarcinomas also had significantly higher NDRG1/Cap43 levels than lung squamous carcinomas (P < 0.01). 22722710 2012
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 Biomarker disease BEFREE Our findings reinforce the idea that NDRG1 plays a metastasis suppressor role in oral and oropharyngeal squamous cell carcinomas and may be a useful marker for these tumors. 22972152 2012
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 AlteredExpression disease LHGDN Decreased expression of NDRG1 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma. 17069588 2006