Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE These data reveal a MAPK pathway-independent switch in response to cAMP signaling during melanoma progression.<b>Implications:</b> The prosurvival mechanism involving the cAMP-EPAC-RAP1 signaling pathway suggest the potential for new targeted therapies in melanoma.<i></i>. 28851815 2017
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE These data suggested that Epac1 in melanoma cells regulates melanoma progression via the HS-FGF2-mediated cell-cell communication. 24725364 2014
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE In human melanoma specimens, mRNA expression of Epac1 was higher in metastatic melanoma than in primary melanoma, suggesting a role for Epac1 in melanoma metastasis. 20551063 2010