Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.320 Biomarker disease CTD_human We identified 14 coding variants in 13 genes, of which 8 variants were in genes (ZBTB7B, ACHE, RAPGEF3, RAB21, ZFHX3, ENTPD6, ZFR2 and ZNF169) newly implicated in human obesity, 2 variants were in genes (MC4R and KSR2) previously observed to be mutated in extreme obesity and 2 variants were in GIPR. 29273807 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.320 Biomarker disease BEFREE The function of Epac1 on obesity was unveiled using Epac1 knockout (KO) mice. 27867203 2017
CUI: C0028754
Disease: Obesity
Obesity 		0.320 Biomarker disease BEFREE While global deletion of Epac1 in mice leads to heightened leptin sensitivity in the hypothalamus and partial protection against high-fat diet (HFD)-induced obesity, the physiological functions of Epac1 in white adipose tissue (WAT) has not been explored. 27381457 2016