YAP1, Yes associated protein 1, 10413

N. diseases: 374; N. variants: 15
Disease: Brain Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.330 Biomarker group CTD_human Thus, we have developed a model proving that neurodevelopmental disorders and brain tumours might originate from the same activation of oncogenes through somatic mutations, and established that YAP activation is a hallmark of malignant brain tumours. 27935819 2017
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.330 Biomarker group BEFREE Thus, we have developed a model proving that neurodevelopmental disorders and brain tumours might originate from the same activation of oncogenes through somatic mutations, and established that YAP activation is a hallmark of malignant brain tumours. 27935819 2017
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.330 AlteredExpression group BEFREE YAP1 has been indicated as an oncoprotein, and overexpression of YAP1 is reported in many human brain tumors, including infiltrating gliomas. 25750037 2015
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.330 Biomarker group BEFREE YAP1 protein was also readily detected in the nuclei of human brain tumors. 21666501 2011