YAP1, Yes associated protein 1, 10413

N. diseases: 374; N. variants: 15
Disease: Osteosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE Mechanically tunable coaxial electrospun models of YAP/TAZ mechanoresponse and IGF-1R activation in osteosarcoma. 31542501 2019
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease BEFREE MiR-1285-3p which was low expressed in osteosarcoma inhibited the proliferation and invasion of osteosarcoma cells via direct targeting YAP1. 31006663 2019
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE On the relationship of YAP and FAK in hMSCs and osteosarcoma cells: Discrimination of FAK modulation by nuclear YAP depletion or YAP silencing. 31376525 2019
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE Therefore, we have uncovered a novel regulatory mechanism by which the APTR/miR-132-3p/YAP1 axis can regulate OS progression. 30317613 2019
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease BEFREE Importantly, HuR and YAP expression was positively correlated in OS tissues. 29597092 2018
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease BEFREE We indicate that lncRNA B4GALT1-AS1 promotes OS cells stemness and migration via recruiting HuR to enhance YAP activity. 30182452 2018
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease BEFREE The upregulated expression of YAP1 in OS tissues was inversely correlated with miR‑625 expression. 29257207 2018
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE The effects of circFAT1/miR-375/YAP1 was evaluated on human osteosarcoma cells growth, apoptosis, migration, invasion and tumorigenesis. 30514309 2018
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 AlteredExpression disease BEFREE These factors are highly expressed in OSs and bind to distinct sites in the YAP1 enhancer. 28905448 2017
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE YAP depletion sharply reduces CSCs and tumorigenicity of osteosarcomas. 25832504 2015
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE Consistent with in vitro findings, nuclear localization of YAP was positively correlated in α-SMA expressing stromal cells of adiposarcoma and osteosarcoma. 26028530 2015
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE Taken together, our results demonstrated that YAP1 is an important regulator of osteosarcoma tumorigenesis and knockdown of YAP1 would be a novel therapeutic strategy for osteosarcoma. 24993351 2014
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.100 Biomarker disease BEFREE Knockdown of YAP1 may inhibit the proliferation and invasion of OS cells through downregulation of the RUNX2 pathway, thereby representing a potential therapeutic target for the treatment of cancer. 23527718 2013