SPON1, spondin 1, 10418

N. diseases: 31; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.020 Biomarker disease BEFREE CKD was a significant interaction term in the associations of NOTCH1 and Spondin-1 with HF. 30557359 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.020 Biomarker disease BEFREE In pooled analysis of both cohorts, higher levels of nine proteins were associated with incident heart failure after adjustment for established risk factors: growth differentiation factor 15 (GDF-15), T-cell immunoglobulin and mucin domain 1 (TIM-1), tumour necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2), spondin-1 (SPON1), matrix metalloproteinase-12 (MMP-12), follistatin (FS), urokinase-type plasminogen activator surface receptor (U-PAR), osteoprotegerin (OPG), and suppression of tumorigenicity 2 (ST2). 28967680 2018