CDX1, caudal type homeobox 1, 1044

N. diseases: 54; N. variants: 1
Disease: Precancerous Conditions ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions 		0.010 AlteredExpression group BEFREE Intestinal-type gastric cancer often results from <i>Helicobacter pylori</i> infection through intestinal metaplasia, a transdifferentiated premalignant phenotype.Because <i>H. pylori</i> virulence factor CagA has been associated with aberrant expression of the transcription factor CDX1, which regulates intestinal differentiation, we explored its relationship with <i>H. pylori</i> infection and function during gastric carcinogenesis in normal gastric epithelial cells and gastric cancer cell lines. 31416838 2019