CDX1, caudal type homeobox 1, 1044

N. diseases: 54; N. variants: 1
Disease: Colon Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.060 Biomarker disease BEFREE Cdx1 exerts a protective role in colon cancer stem cells, which play a crucial role in chemoresistance to paclitaxel through activation of autophagy. 23624503 2013
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.060 AlteredExpression disease BEFREE This inhibitory effect is dose-dependent and is observed in different colon cancer cell lines, and the degree of inhibition correlates with the ability of Cdx1 to reduce cell proliferation. 15215241 2004
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.060 Biomarker disease BEFREE Here we have analysed the pattern of Cdx1 in human colon cancer progression. 12970739 2003
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.060 AlteredExpression disease BEFREE This study tests the hypothesis that Cdx1 expression inhibits colon cancer cell proliferation by reducing cyclin D1 gene expression. 14508520 2003
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.060 AlteredExpression disease BEFREE CDX1 expression is developmentally and spatially regulated, and its expression is aberrantly down-regulated in colorectal cancers and colon cancer-derived cell lines. 12124393 2002
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.060 Biomarker disease BEFREE Deregulated expression of homeobox-containing genes, HOXB6, B8, C8, C9, and Cdx-1, in human colon cancer cell lines. 10833444 2000