MCRS1, microspherule protein 1, 10445

N. diseases: 37; N. variants: 1
Disease: Fibrosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0016057
Disease: Fibrosarcoma
Fibrosarcoma 		0.010 AlteredExpression disease BEFREE Specifically, ectopic expression of MSP58 in normal human IMR90 and Hs68 diploid fibroblasts, the H184B5F5/M10 mammary epithelial cell line, HT1080 fibrosarcoma cells, primary mouse embryonic fibroblasts, and immortalized NIH3T3 fibroblasts resulted in induction of premature senescence, an enlarged and flattened cellular morphology, and increased senescence-associated β-galactosidase activity. 22563078 2012