TRIM38, tripartite motif containing 38, 10475

N. diseases: 12; N. variants: 8
Disease: Virus Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.020 Biomarker group BEFREE Here, we show that TRIM38 positively regulates MDA5- and RIG-I-mediated induction of downstream genes and acts as a SUMO E3 ligase for their dynamic sumoylation at K43/K865 and K96/K888, respectively, before and after viral infection. 28250012 2017
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.020 AlteredExpression group BEFREE Our observations demonstrate that TRIM38 has E3 ubiquitin ligase activity and can be degraded during virus infection. 21306652 2011