Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Nose and throat carriage of MRSA and PVL-SA was low among recruits, despite a high incidence of SSTIs being reported, particularly cellulitis. 31357012 2020
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 GeneticVariation group BEFREE To overcome the increasing difficulties in the clinical management of SSTI due to MRSA, new prophylactic and therapeutic approaches are urgently needed and a preventive vaccine would be welcome. 31299217 2019
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE These infections were chiefly SSTIs, although urinary tract infections were also noted.Incidences of CO-MRSA blood-stream infections and outpatient skin and soft tissue infections have been increasing with time, except in Tasmania. 30805180 2019
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 AlteredExpression group BEFREE The LA-S. aureus infected mice had decreased IL-1β protein levels compared with CA-MRSA-infected mice (p < 0.05), suggesting a suboptimal host response to LA-S. aureus SSTIs. 31043631 2019
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Travel-associated CA-MRSA SSTI is a transmissible condition that leads to medical consultations and colonization of the infected host. 30315958 2019
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 GeneticVariation group BEFREE We conducted a study to determine in vitro susceptibility to vancomycin, daptomycin, linezolid and tedizolid in MRSA clinical isolates from adult patients with skin and soft tissue infections. 28432878 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Ceftaroline MICs were determined by reference BMD and by Etest for 1242 MSSA and MRSA isolates collected between February and May 2012 from adult patients with community-acquired pneumonia or complicated skin and soft tissue infections; tests were performed across six European laboratories. 27798220 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE LA-MRSA CC398 caused 24.3 BSIs per 1000 SSTIs among people with no livestock contact, which is similar to the ratio observed for other types of MRSA. 28575216 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Meanwhile, case reports, case series and few studies have demonstrated the capability of LA-MRSA to cause all types of infections attributed to S. aureus in general including fatal courses.Human infections observed comprise e.g. bacteremia, pneumonia, osteomyelitis, endocarditis and many manifestations of skin and soft tissue infections. 26644311 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE MRSA skin and soft-tissue infection (SSTI) incidence density decreased in adults (-3.5%; P<.001) and children (-2.9%; P=.004). 28903801 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Culturing of pus-producing SSTIs is crucial for providing adequate antimicrobials and elucidating MRSA epidemiology. 27677279 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 GeneticVariation group BEFREE High burden of complicated skin and soft tissue infections in the Indigenous population of Central Australia due to dominant Panton Valentine leucocidin clones ST93-MRSA and CC121-MSSA. 28592231 2017
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE We previously showed that MRSA isolates from soft tissue infection (SSTI) produced significantly higher levels of PSM than MRSA isolates from hospital-acquired pneumonia (HAP) or infective endocarditis (IE). 26778460 2016
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Staphylococcus aureus(CA-MRSA) isolates with skin and soft tissue infections (SSTIs). 27060098 2016
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE We collected MRSA strains isolated from outpatients with skin and soft-tissue infection (SSTI) at 107 medical facilities from 24 prefectures in 2010 and 2012. 25789579 2015
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Our results suggested intrafamilial transmission of MRSA could be initial phenomenon of wide transmission in a community, therefore CA-MRSA SSTI in children and their family members should be monitored closely in order to notice the spread of highly pathogenic and transmittable strains. 26091885 2015
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE The predominance of SCCmec type IV or V CA-MRSA in soft tissue infection has also been indicated in Northern Taiwan. 26167865 2015
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE We characterized 45 non-duplicate CA-MRSA strains implicated mainly in skin and soft tissue infections (SSTIs) in a tertiary care hospital in Mysore, South India. 26044198 2015
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Thirteen clinical CA-MRSA isolates recovered from patients presenting with skin and soft tissue infections to nine primary care clinics in the South Texas Ambulatory Research Network between 2010 and 2013. 25644979 2015
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Two-hundred MRSA strains from inpatients with healthcare-associated (HA) and 100 MRSA strains from outpatients with community-associated (CA) skin and soft tissue infections (SSTIs) were tested for antimicrobial susceptibility, staphylococcal cassette chromosome mec (SCCmec) typing, Panton-Valentine leucocidin (PVL) toxin, seh and arcA genes. 24690229 2015
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Tigecycline demonstrated comparable efficacy for treatment of MRSA soft tissue infections regardless of infection type, SCCmec, or PVL status. 24725736 2014
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Compared to HA-MRSA-HO isolates, the CA-MRSA and HA-MRSA-CO isolates were associated with a higher proportion of skin and soft tissue infections (81.8% and 65.3% vs. 40.5%, p=0.001 and p=0.002) as well as lesser rate of resistance to ciprofloxacin (33.3% and 50.9% vs. 74.4%, p<0.001 and p=0.002), gentamicin (44.4% and 64.4% vs. 84.6%, p<0.001 and p=0.002), and trimethoprim/sulfamethoxazole (33.3% and 42.4% vs. 58.1%, p=0.02 and p=0.048), and a lower 30-day all-cause mortality rate (7.4% and 0% vs. 20.9%, p<0.001). 24961181 2014
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE After infection control measures and prolonged decontamination have been implemented with a high adherence, six patients remained sustained CA-MRSA USA300 carriers, including one who developed mupirocin resistance and six who experienced minor CA-MRSA-related SSTIs. 24816900 2014
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE Twenty MRSA isolates were detected from CAI, 17 were from skin and soft-tissue infections and 3 from other infections. 23731504 2013
CUI: C0149778
Disease: Soft Tissue Infection
Soft Tissue Infection
0.100 Biomarker group BEFREE In particular, the USA300 epidemic clone has emerged and now represents the cause of as much as 98% of CA-MRSA skin and soft tissue infections in the United States. 23698534 2013