HOXB13, homeobox B13, 10481

N. diseases: 90; N. variants: 3
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 GeneticVariation group BEFREE Although HOXB13 also plays a role in breast tumor progression, the association of HOXB13 p.G84E with breast cancer risk is less evident. 27424772 2016
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker group CTD_human Human HOX gene disorders. 24239177 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker group LHGDN Exploring the two-gene ratio in breast cancer--independent roles for HOXB13 and IL17BR in prediction of clinical outcome. 17453342 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker group LHGDN In primary breast tumors, HOXB13 expression correlated negatively, and IL17BR and CHDH expression correlated positively, with ER status, and all three genes exhibited an ER-dependent correlation pattern with HER2 status that differs from PR and PS2, two canonical estrogen-regulated genes. 17975144 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker group LHGDN The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer. 17008703 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 AlteredExpression group LHGDN Genomic testing for sensitivity of breast cancer to hormonal therapy. 16609001 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 AlteredExpression group LHGDN A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen. 16609019 2006