NXF1, nuclear RNA export factor 1, 10482

N. diseases: 141; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.030 Biomarker group BEFREE This conservation of BNLF2a function during evolution of EBV implies an important role for the viral TAP inhibitor in preventing T cell recognition during viral infection. 22013037 2012
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.030 Biomarker group BEFREE These data may explain why TAP-deficient individuals live normal life spans without any increased susceptibility to viral infections. 22298786 2012
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.030 Biomarker group BEFREE These observations suggest that in the TAP-deficient patients, CD8+ alphabeta T cells could mature and be recruited in immune responses to mediate HLA class I-restricted cytotoxic defense against viral infections. 9144467 1997