ZNRD2, zinc ribbon domain containing 2, 10534

N. diseases: 311; N. variants: 7
Disease: Liver Cirrhosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.030 Biomarker disease BEFREE miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients. 22446332 2012
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.030 AlteredExpression disease BEFREE A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC. miR-221/222, the most up-regulated miRNAs in tumor samples, are shown to target the CDK inhibitor p27 and to enhance cell growth in vitro. 20018759 2010
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.030 AlteredExpression disease BEFREE In addition, there was a significant correlation between the expression of p27 protein and p27mRNA in the integrated group of normal liver and liver cirrhosis. 16052694 2005