PROCR, protein C receptor, 10544

N. diseases: 110; N. variants: 20
Disease: Hemophilia, NOS ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684275
Disease: Hemophilia, NOS
Hemophilia, NOS 		0.030 AlteredExpression disease BEFREE Overall, our data indicate that EPCR levels influence the hemostatic effect of rFVIIa in treating hemophilia. 28932824 2017
CUI: C0684275
Disease: Hemophilia, NOS
Hemophilia, NOS 		0.030 Biomarker disease BEFREE Comprehensive understanding of EPCR may lead to development of novel therapeutic modalities in treating hemophilia, inflammation, cerebral malaria, and cancer. 25049281 2014
CUI: C0684275
Disease: Hemophilia, NOS
Hemophilia, NOS 		0.030 Biomarker disease BEFREE Because mFVIIa-FMR models the TF-dependent and EPCR binding properties of rhFVIIa, our data unmask a novel contribution of EPCR on the action of rhFVIIa administration in hemophilia, prompting the rational design of improved and safer rhFVIIa therapeutics. 24957146 2014