OLFM4, olfactomedin 4, 10562

N. diseases: 89; N. variants: 3
Disease: Malignant Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 AlteredExpression group BEFREE Up-regulation of OLFM4 has been detected in the <i>Helicobacter pylori</i> (<i>H. pylori</i>)-infected gastric mucosa, inflammatory bowel disease tissue and gastrointestinal malignancies, including gastric cancer, colorectal cancer, pancreatic cancer and gallbladder cancer. 29740203 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 Biomarker group BEFREE The background for this high plasma level is not known, but must be taken into account if OLFM4 is used as biomarker for GI cancers. 26416558 2015
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 AlteredExpression group BEFREE OLFM4 expression level in NSCLC lesions was strongly correlated with pathologic grade (P = .017), lymph node metastasis (P = .012), peritumor intravascular cancer emboli (P = .03), and smoking status (P < .001). 25771901 2015
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 AlteredExpression group BEFREE Overall, suppression of OLFM4 expression may be a promising strategy in the development of novel cancer therapeutic drugs. 26398045 2015
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 Biomarker group BEFREE In addition, OLFM4 is associated with cancer adhesion and metastasis. 21067260 2011
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 AlteredExpression group BEFREE Measurement of Reg IV and GW112 levels in sera indicated a sensitivity of 57% for detection of cancer. 19261089 2009
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.070 AlteredExpression group BEFREE Enhanced hGC-1 expression was more frequently seen in intestinal-type adenocarcinoma, whereas loss of expression tended to occur in the diffuse type. hGC-1 was highly expressed in well or moderately differentiated cancers and was remarkably reduced or lost in poorly differentiated or undifferentiated tumours. 17650212 2007