CELP, carboxyl ester lipase pseudogene, 1057

N. diseases: 16; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149521
Disease: Pancreatitis, Chronic
Pancreatitis, Chronic
0.330 Biomarker disease BEFREE It has previously been reported in a European case-control study with patients from Germany and France that CEL-HYB1, a hybrid allele of the carboxyl ester lipase (CEL) gene and its pseudogene CELP, increases susceptibility to chronic pancreatitis (CP). 31036489 2019
CUI: C0149521
Disease: Pancreatitis, Chronic
Pancreatitis, Chronic
0.330 GeneticVariation disease BEFREE A hybrid allele between the carboxyl ester lipase gene (CEL) and its pseudogene, CELP (called CEL-HYB), generated by nonallelic homologous recombination between CEL intron 10 and CELP intron 10', was found to increase susceptibility to chronic pancreatitis in a case-control study of patients of European ancestry. 26946345 2016
CUI: C0149521
Disease: Pancreatitis, Chronic
Pancreatitis, Chronic
0.330 Biomarker disease CTD_human A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. 25774637 2015
CUI: C0149521
Disease: Pancreatitis, Chronic
Pancreatitis, Chronic
0.330 Biomarker disease BEFREE A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. 25774637 2015
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.030 GeneticVariation phenotype BEFREE We established a new choriocarcinoma cell line, induced choriocarcinoma cell-1 (iC3-1), which mimics the clinical pathohistology in vivo, to examine the tumorigenesis and pathogenesis of choriocarcinoma. 24424471 2014
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.030 Biomarker phenotype BEFREE In this study, to clarify the genetic characteristics of iC(3)-1 and to explore the tumorigenesis mechanism, we examined the gene profile of iC(3)-1 compared to those of existing cell lines and normal placental tissue. 23199791 2013
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.030 Biomarker phenotype BEFREE At cellular level, what we have achieved is the shifting of the Stem Cell 1 population, highly susceptible to cancer, to a population of Stem Cell 2 that is refractory to carcinogenesis. 17882673 2007
CUI: C0008497
Disease: Choriocarcinoma
Choriocarcinoma
0.020 Biomarker disease BEFREE In this study, the alterations of glycan structures in the development of choriocarcinoma were examined by performance of comprehensive glycan profiling in clinical samples and in iC3-1 cells using a conventional microarray and the recently introduced lectin microarray. 24424471 2014
CUI: C0008497
Disease: Choriocarcinoma
Choriocarcinoma
0.020 AlteredExpression disease BEFREE In summary, the gene expression profile of iC(3)-1 suggests that studies using this cell line can make an important contribution to improved understanding of choriocarcinoma tumorigenesis. 23199791 2013
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.020 Biomarker group BEFREE At cellular level, what we have achieved is the shifting of the Stem Cell 1 population, highly susceptible to cancer, to a population of Stem Cell 2 that is refractory to carcinogenesis. 17882673 2007
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.020 Biomarker group BEFREE At cellular level, what we have achieved is the shifting of the Stem Cell 1 population, highly susceptible to cancer, to a population of Stem Cell 2 that is refractory to carcinogenesis. 17882673 2007
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.020 Biomarker group BEFREE (2002) Cancer Cell 1, 19-30), little is known about the signaling pathways leading to changes in the apoptotic threshold in cancer cells. 14766752 2004
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.020 Biomarker group BEFREE (2002) Cancer Cell 1, 19-30), little is known about the signaling pathways leading to changes in the apoptotic threshold in cancer cells. 14766752 2004
Respiratory syncytial virus bronchiolitis
0.010 Biomarker disease BEFREE Increased T-helper Cell 2 Response in Infants With Respiratory Syncytial Virus Bronchiolitis Hospitalized Outside Epidemic Peak. 31815840 2020
CUI: C0017536
Disease: Giardiasis
Giardiasis
0.010 Biomarker disease BEFREE Increased Innate Lymphoid Cell 3 and IL-17 Production in Mouse Lamina Propria Stimulated with Giardia lamblia. 31284344 2019
CUI: C0018995
Disease: Hemochromatosis
Hemochromatosis
0.010 Biomarker disease BEFREE Haemochromatosis: Pathophysiology and the red blood cell1. 29660923 2018
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.010 Biomarker disease BEFREE Proinflammatory CX3CR1+CD59+Tumor Necrosis Factor-Like Molecule 1A+Interleukin-23+ Monocytes Are Expanded in Patients With Ankylosing Spondylitis and Modulate Innate Lymphoid Cell 3 Immune Functions. 29869839 2018
CUI: C0276653
Disease: Invasive Pulmonary Aspergillosis
Invasive Pulmonary Aspergillosis
0.010 Biomarker disease BEFREE Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8<sup>+</sup> T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis. 28485322 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.010 Biomarker phenotype BEFREE Among HPV16-positive patients with oropharyngeal carcinoma, metastases to regional lymph nodes were observed in 100 % (17/17) and 68 % (40/58) for those with <1 HPV16 copy cell-1 and >1 HPV16 copy cell-1, respectively (P=0.007). 27667722 2016
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.010 Biomarker disease BEFREE Among HPV16-positive patients with oropharyngeal carcinoma, metastases to regional lymph nodes were observed in 100 % (17/17) and 68 % (40/58) for those with <1 HPV16 copy cell-1 and >1 HPV16 copy cell-1, respectively (P=0.007). 27667722 2016
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.010 Biomarker group BEFREE Among HPV16-positive patients with oropharyngeal carcinoma, metastases to regional lymph nodes were observed in 100 % (17/17) and 68 % (40/58) for those with <1 HPV16 copy cell-1 and >1 HPV16 copy cell-1, respectively (P=0.007). 27667722 2016
Mixed follicular and papillary thyroid carcinoma
0.010 Biomarker disease BEFREE CXC chemokine receptor 4 immunodetection in the follicular variant of papillary thyroid carcinoma: comparison to galectin-3 and hector battifora mesothelial cell-1. 20450430 2010
CUI: C1701940
Disease: Pneumonia, Ventilator-Associated
Pneumonia, Ventilator-Associated
0.010 Biomarker disease BEFREE Soluble triggering receptor expressed on myeloid cell-1 is increased in patients with ventilator-associated pneumonia: a preliminary report. 17505044 2007
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.010 Biomarker group BEFREE Seven of 9 alterations in p16/CDKN2 and p15/MTS2 were observed in serous (3 of 12), endometrioid (3 of 9) and clear-cell (1 of 4) carcinomas. 8980248 1996