Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 GeneticVariation phenotype BEFREE Moreover, p16 and p15 gene deletion was related to tumor progression and might have a role in bilharzial bladder carcinogenesis. 15590562 2004
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 PosttranslationalModification phenotype BEFREE Our results show that although p16 and/or p15 methylation is involved in non-Hodgkin's and Hodgkin's tumors that share morphological and phenotypic features, differences in incidence, pattern of methylation, and implication in tumor progression are observed. 12213729 2002
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 PosttranslationalModification phenotype BEFREE Our data underscore the important role(s) of p15 and p16 methylation in hepatocarcinogenesis and tumor progression. 10999738 2000
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 Biomarker phenotype BEFREE Our results indicate that loss of the p16 and p15 genes may be involved in tumor progression in human gliomas, especially in the development of glioblastoma, that this loss may give growth advantage to the cells in culture, and that it is not the result of culture artifacts. 7497469 1995
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 Biomarker phenotype BEFREE Collectively, these observations suggest a role for p15 in growth regulation, but a limited role for p15 in tumor progression. 7675459 1995