SORBS1, sorbin and SH3 domain containing 1, 10580

N. diseases: 124; N. variants: 28
Disease: Diabetes Mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.050 Biomarker group BEFREE Neither diabetes duration nor haemoglobin A1c differed according to CAP or LSM values. 31612634 2020
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.050 Biomarker group BEFREE These findings supported that SORBS1 gene participates in the pathogenesis of diabetes. 30002559 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.050 GeneticVariation group BEFREE T228A polymorphism of SORBS1 was not associated with the prevalence of diabetes. 18394047 2008
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.050 GeneticVariation group BEFREE An association study showed that a missense variant of the SORBS1 gene is protective against obesity and diabetes. 12849814 2003
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.050 GeneticVariation group BEFREE In conclusion, our results suggest that the A228 allele of the T228A polymorphism of the SORBS1 gene is a protective factor for both obesity and diabetes, and also imply that the SORBS1 gene plays an important role in the pathogenesis of human disorders with insulin resistance. 11532984 2001