ARID3B, AT-rich interaction domain 3B, 10620

N. diseases: 46; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005890
Disease: Body Height
Body Height 		0.100 GeneticVariation phenotype GWASCAT Characterizing rare and low-frequency height-associated variants in the Japanese population. 31562340 2019
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation disease GWASCAT Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate. 28054174 2017
CUI: C0008925
Disease: Cleft Palate
Cleft Palate 		0.100 GeneticVariation disease GWASCAT Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate. 28054174 2017
CUI: C0014175
Disease: Endometriosis
Endometriosis 		0.100 GeneticVariation disease GWASCAT New variants near RHOJ and C2, HLA-DRA region and susceptibility to endometriosis in the Polish population-The genome-wide association study. 28881265 2017
CUI: C0265240
Disease: Goldenhar Syndrome
Goldenhar Syndrome 		0.100 GeneticVariation disease GWASCAT Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia. 26853712 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE The DNA-binding protein AT-Rich Interactive Domain 3B (ARID3B) is elevated in ovarian cancer and increases tumor growth in a xenograft model of ovarian cancer. 26121572 2015
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE To understand the extent that ARID3B participates in tumor development, we assessed protein expression of ARID3B in normal adult and malignant tissues. 24704276 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE To assess how ARID3B contributes to the increased tumor growth in vivo, we identified ARID3B induced genes in tumor ascites cells. 25327563 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE Nuclear ARID3B staining positively correlated with estrogen receptor (ER) status and negatively correlated with tumor grade, mitotic index and ERBB2 status of the patients. 25120063 2014
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.030 Biomarker disease BEFREE The DNA-binding protein AT-Rich Interactive Domain 3B (ARID3B) is elevated in ovarian cancer and increases tumor growth in a xenograft model of ovarian cancer. 26121572 2015
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.030 AlteredExpression disease BEFREE Recently we reported that the DNA binding protein ARID3B is overexpressed in human ovarian tumors. 25327563 2014
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.030 AlteredExpression disease BEFREE ARID3B is a DNA binding protein that is overexpressed in neuroblastoma and ovarian cancer. 24704276 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.020 Biomarker disease BEFREE These results suggest that SZ and BDP groups have different patterns of conflict adaptation. 30025790 2018
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.020 Biomarker disease BEFREE We compared: (1) Psychosis Model (psychosis, non-psychosis), where the psychosis group included SZ, SA, and BDP+, and the non-psychosis group included BDP- and HC; (2) Schizophrenia Model (SZ, non-SZ); and (3) DSM Model (SZ, SA, BD, HC). 29768190 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.020 Biomarker group BEFREE These results highlight a chromatin-dependent mechanism where let-7 regulates cancer stemness through ARID3B. 26776511 2016
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.020 Biomarker group BEFREE These results highlight a chromatin-dependent mechanism where let-7 regulates cancer stemness through ARID3B. 26776511 2016
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.020 Biomarker disease BEFREE The DNA-binding protein AT-Rich Interactive Domain 3B (ARID3B) is elevated in ovarian cancer and increases tumor growth in a xenograft model of ovarian cancer. 26121572 2015
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial 		0.020 Biomarker disease BEFREE The DNA-binding protein AT-Rich Interactive Domain 3B (ARID3B) is elevated in ovarian cancer and increases tumor growth in a xenograft model of ovarian cancer. 26121572 2015
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.020 AlteredExpression disease BEFREE Increased nuclear expression of ARID3B was confirmed in breast cancer-derived cell lines expressing ERα. 25120063 2014
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.020 Biomarker group BEFREE Moreover, ARID3B increased the number of CD133+ (a cancer stem cell marker) cells compared to control cells. 25327563 2014
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.020 AlteredExpression disease BEFREE ARID3B is a DNA binding protein that is overexpressed in neuroblastoma and ovarian cancer. 24704276 2014
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.020 AlteredExpression disease BEFREE Increased nuclear expression of ARID3B was confirmed in breast cancer-derived cell lines expressing ERα. 25120063 2014
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		0.020 AlteredExpression disease BEFREE ARID3B is a DNA binding protein that is overexpressed in neuroblastoma and ovarian cancer. 24704276 2014
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.020 AlteredExpression disease BEFREE ARID3B is a DNA binding protein that is overexpressed in neuroblastoma and ovarian cancer. 24704276 2014
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.020 Biomarker group BEFREE Moreover, ARID3B increased the number of CD133+ (a cancer stem cell marker) cells compared to control cells. 25327563 2014