CD226, CD226 molecule, 10666

N. diseases: 124; N. variants: 22
Disease: Immunosuppression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.010 AlteredExpression disease BEFREE The costimulatory receptor CD226 was downregulated in TIGIT<sup>+</sup> compared with TIGIT<sup>-</sup> CD8 FL T cells, further skewing the balance toward immunosuppression.<b>Conclusions:</b> TIGIT blockade is a relevant strategy for improved immunotherapy in FL. 29217528 2018