TNFSF13B, TNF superfamily member 13b, 10673

N. diseases: 282; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031099
Disease: Periodontitis
Periodontitis
0.020 Biomarker disease BEFREE Studies in patients indicate that B cells and plasma cells, together with osteoclastogenic factors (RANKL and osteoprotegerin) and specific cytokines involved in their growth and differentiation (BAFF and APRIL) participate in the induction of the pathological bone loss in periodontitis. 28013554 2017
CUI: C0031099
Disease: Periodontitis
Periodontitis
0.020 AlteredExpression disease BEFREE We show that, relative to healthy controls, the expression of APRIL and BLyS mRNA and protein was upregulated in natural and experimental periodontitis in humans and mice, respectively. 26150532 2015