Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
In the field of lipoprotein metabolism and cardiovascular disease several gene polymorphisms for key proteins, such as apoproteins (apo) E, B, A-IV and C-III, LDL receptor, microsomal transfer protein (MTP), fatty acid-binding protein (FABP), cholesteryl ester transfer protein (CETP), lipoprotein lipase and hepatic lipase, have been identified and linked to variable responses to diets.
|
12691171 |
2002 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The relationship of ACE and CETP gene polymorphisms with cardiovascular disease in a cohort of Asian Indian patients with and those without type 2 diabetes.
|
21185205 |
2012 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
We aimed to identify independent genetic determinants of circulating CETP (cholesteryl ester transfer protein) to assess causal effects of variation in CETP concentration on circulating lipid concentrations and cardiovascular disease risk.
|
29728394 |
2018 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
A CETP polymorphism improves the diagnostic power of clinical examination in patients with cardiovascular disease.
|
20458649 |
2010 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
A cholesteryl ester transfer protein (CETP) genotype (V/V homozygosity for I405V, NCBI dbSNP rs5882) has been associated with preservation of cognitive function in old age, in addition to its associations with exceptional longevity and cardiovascular disease.
|
17531380 |
2007 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The synthesis of available evidence demonstrates that the CETP TaqIB polymorphism protects against composite ischemic CVD risk and is associated with a higher HDL-C concentration in both Asians and Caucasians.
|
27608031 |
2016 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Previously, the beneficial effect of an advantageous cholesteryl ester transfer protein (CETP-VV) genotype on lipoprotein particle size in association with decreased metabolic and cardiovascular diseases, as well as with better cognitive function, have been demonstrated.
|
17784782 |
2007 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
This study investigated the relation between a genetic variant in the CETP gene and measures of insulin resistance and incident T2DM in patients with manifest cardiovascular disease (CVD).
|
26318399 |
2015 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The CETP B1B1 genotype may influence the susceptibility to CVD in Taiwan.
|
18287799 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
High levels of plasma high-density lipoprotein-cholesterol (HDL-C) are inversely associated with the risk of atherosclerosis and other cardiovascular diseases; thus, pharmacological inhibition of cholesteryl ester transfer protein (CETP) is considered to be a therapeutic method of raising HDL-C levels.
|
29317793 |
2017 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
LHGDN |
TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia.
|
15856070 |
2005 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Cholesteryl ester transfer protein B1B1 genotype is associated with a parental history of cardiovascular diseases in Taiwanese people.
|
18287799 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Concomitant presence of both, CETP B1 and NOS3 T allele, associated with increased risk of T2DM, CVD and CVD in T2DM by 8.36-, 6.33- and 7.87-fold, respectively, while concomitant presence of ANGPTL8 variant with either CETP B1 or NOS3 T allele was not associated with increased risk of T2DM or CVD.
|
29973202 |
2018 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Different therapies have been suggested and some are used to treat elevated lipoprotein(a) levels such as niacin, PCSK9 inhibitors, and CETP inhibitors; however, to date, no randomized controlled trial has demonstrated that lowering of lipoprotein(a) leads to lower risk of cardiovascular disease.
|
31111240 |
2019 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Cholesteryl ester transfer protein (CETP) plays a major role in lipid metabolism, but studies on the association of CETP polymorphisms with risks of cardiovascular disease are inconsistent.
|
23039379 |
2012 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Common variation in the CETP gene and the implications for cardiovascular disease and its treatment: an updated analysis.
|
18518852 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Common variation in the CETP gene and the implications for cardiovascular disease and its treatment: an updated analysis.
|
18518852 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Cholesteryl ester transfer protein genetic polymorphisms, HDL cholesterol, and subclinical cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis.
|
18243217 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia.
|
15856070 |
2005 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Cholesteryl ester transfer protein (CETP) I405V polymorphism and cardiovascular disease in eastern European Caucasians - a cross-sectional study.
|
27439317 |
2016 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Human cholestryl ester transfer protein (TaqIB) polymorphism among Filipinos with cardiovascular risk factors.
|
17587762 |
2007 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Mendelian randomization studies indicate that most genetic variants that affect a range of pathways that increase plasma HDL-C levels are not usually associated with reduced risk of cardiovascular disease, with some exceptions, such as cholesteryl ester transfer protein variants.
|
28795686 |
2018 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction.
|
18957472 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Thrombospondin-4 (TSP-4), a matricellular protein of vessel walls associated with inflammation, was investigated in terms of CVD risk using multivariable modelling with a well-characterised functional genetic polymorphism of THBS4 (rs1866389" genes_norm="7060">A387P, rs1866389) along with previously demonstrated risk-related functional genetic polymorphisms of CYBA (C242T, rs4673) and CETP (TaqIB, rs708272), and a set of blood markers.
|
22011848 |
2011 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
A lower cholesterol concentration in the HDL fraction in children with a family history of cardiovascular system diseases was determined by polymorphism of the CETP gene.
|
24091356 |
2013 |