Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
In the field of lipoprotein metabolism and cardiovascular disease several gene polymorphisms for key proteins, such as apoproteins (apo) E, B, A-IV and C-III, LDL receptor, microsomal transfer protein (MTP), fatty acid-binding protein (FABP), cholesteryl ester transfer protein (CETP), lipoprotein lipase and hepatic lipase, have been identified and linked to variable responses to diets.
|
12691171 |
2002 |
Cardiovascular Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
In terms of new information, three topics are presented: (1) new findings related to classical candidate genes, such as apolipoprotein E, cholesteryl ester transfer protein and hepatic lipase; (2) recent reports related to new loci that have joined the growing list of cardiovascular disease candidate genes (i.e.
|
12544661 |
2003 |
Cardiovascular Diseases
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Since the identification of cholesteryl ester transfer protein (CETP), its role in the modulation of HDL levels and cardiovascular disease has been debated.
|
12639975 |
2003 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
LHGDN |
TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia.
|
15856070 |
2005 |
Cardiovascular Diseases
|
0.400 |
Biomarker
|
group |
LHGDN |
To better understand the role of cholesteryl ester transfer protein (CETP) in cardiovascular disease, nine polymorphisms spanning the gene from the upstream promoter region to beyond the 3'UTR were genotyped in 2553 individuals from multiple ethnic groups and with different cardiovascular disease profiles.
|
15939053 |
2005 |
Cardiovascular Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
These results replicate some earlier findings and also help to explain some of the apparent contradictions in the literature surrounding the role of CETP in modulating HDL-C and cardiovascular disease.
|
15939053 |
2005 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia.
|
15856070 |
2005 |
Cardiovascular Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Cholesteryl ester transfer protein (CETP) is an important modulator of high density lipoprotein cholesterol in humans and thus considered to be a therapeutic target for preventing cardiovascular disease.
|
15681846 |
2005 |
Cardiovascular Diseases
|
0.400 |
Biomarker
|
group |
CTD_human |
Candidate gene polymorphism in cardiovascular disease: the BIP cohort.
|
16544732 |
2006 |
Cardiovascular Diseases
|
0.400 |
Biomarker
|
group |
LHGDN |
CETP levels rather than polymorphisms as markers of coronary risk: healthy athlete with high HDL-C and coronary disease--effectiveness of probucol.
|
16563399 |
2006 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
A cholesteryl ester transfer protein (CETP) genotype (V/V homozygosity for I405V, NCBI dbSNP rs5882) has been associated with preservation of cognitive function in old age, in addition to its associations with exceptional longevity and cardiovascular disease.
|
17531380 |
2007 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Previously, the beneficial effect of an advantageous cholesteryl ester transfer protein (CETP-VV) genotype on lipoprotein particle size in association with decreased metabolic and cardiovascular diseases, as well as with better cognitive function, have been demonstrated.
|
17784782 |
2007 |
Cardiovascular Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Cholesteryl ester transfer protein (CETP) plays a key role in the metabolism of high-density lipoprotein (HDL), a strong, inverse, independent risk factor for cardiovascular disease.
|
17949364 |
2007 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Human cholestryl ester transfer protein (TaqIB) polymorphism among Filipinos with cardiovascular risk factors.
|
17587762 |
2007 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Polymorphisms in the hepatic lipase (LIPC -514C > T) and cholesteryl ester transfer protein (CETP I405V) genes affect high-density lipoprotein cholesterol (HDL-c) levels, but their relationship with cardiovascular disease and their combined effect is unclear.
|
17440012 |
2007 |
Cardiovascular Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Further studies are necessary for understanding of the role of CETP in lipid metabolism and the development of novel therapies involving a combination of strategies for treatment of atherosclerosis and cardiovascular disease.
|
18620517 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The CETP B1B1 genotype may influence the susceptibility to CVD in Taiwan.
|
18287799 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Cholesteryl ester transfer protein B1B1 genotype is associated with a parental history of cardiovascular diseases in Taiwanese people.
|
18287799 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Common variation in the CETP gene and the implications for cardiovascular disease and its treatment: an updated analysis.
|
18518852 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Common variation in the CETP gene and the implications for cardiovascular disease and its treatment: an updated analysis.
|
18518852 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Cholesteryl ester transfer protein genetic polymorphisms, HDL cholesterol, and subclinical cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis.
|
18243217 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction.
|
18957472 |
2008 |
Cardiovascular Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
A CETP polymorphism improves the diagnostic power of clinical examination in patients with cardiovascular disease.
|
20458649 |
2010 |
Cardiovascular Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
In this regard, apo-AI analogs and CETP inhibitors dalcetrapib and anacetrapib have aroused a great interest and opened new expectations in the treatment of CVD.
|
21985435 |
2011 |
Cardiovascular Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
The concept that HDL cholesterol raising through inhibition of CETP may ameliorate CVD risk has been challenged by the failure of the CETP inhibitor, torcetrapib.
|
20645987 |
2011 |