CFL1, cofilin 1, 1072

N. diseases: 153; N. variants: 6
Disease: Bladder Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.030 AlteredExpression disease BEFREE qRT-PCR and Western blotting analysis showed that Cofilin 1 expression was up-regulated in both bladder cancer tissues and cell lines compared with normal. 30858759 2019
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.030 Biomarker disease BEFREE Thus, TCF7L2 contributed to Cofilin 1-induced promotion of bladder cancer development by binding to the Cofilin 1 promoter and increasing its expression. 29190896 2017
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.030 Biomarker disease BEFREE Our study indicates that Cofilin 1 holds an important position in the development and progression of human bladder cancer, and this gene might become a novel target in the diagnosis and treatment of human bladder cancer. 27768223 2017