CFL1, cofilin 1, 1072

N. diseases: 153; N. variants: 6
Disease: Tumor Progression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 AlteredExpression phenotype BEFREE However, the roles of the CLOCK and BMAL1 genes in the regulation of tumor progression via the RHOA-ROCK-CFL pathway remain largely unclear. 30287810 2018
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 AlteredExpression phenotype BEFREE It was detected that high-fat diet feeding promoted cancer progression in transgenic mice with prostate cancer, with increased expressions of β-parvin (P=0.038) and cofilin 1 (P=0.018). 30250560 2018
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 AlteredExpression phenotype BEFREE Immune-complex level of cofilin-1 in sera is associated with cancer progression and poor prognosis in pancreatic cancer. 28161904 2017
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 AlteredExpression phenotype BEFREE Our study suggested that positive CFL1 and Arp3 expression are closely related to tumor progression, metastasis, and poor prognosis of gallbladder cancer. 23320827 2013
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 Biomarker phenotype BEFREE Cofilin-1 (CFL1), a critical modulator of the actin cystoskeleton, is associated with tumour progression, cell motility, cell adhesion, cell invasion and angiogenesis. 20713416 2010
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 GeneticVariation phenotype BEFREE These results show that p18 alteration is involved in tumor progression in a subset of oligodendrogliomas. 10994011 2000