DisGeNET - a database of gene-disease associations

IQGAP2, IQ motif containing GTPase activating protein 2, 10788

N. diseases: 46; N. variants: 10

Disease: Stomach Carcinoma ×

Source: ALL

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0699791
Disease:	Stomach Carcinoma

Stomach Carcinoma

0.020

Biomarker

disease

BEFREE

Loss of IQGAP2 contributes to the tumorigenesis of hepatocellular carcinoma and gastric cancer.

22406297

2012

CUI:	C0699791
Disease:	Stomach Carcinoma

Stomach Carcinoma

0.020

AlteredExpression

disease

BEFREE

We found that IQGAP2 protein expression was lost in 5 of the 9 gastric cancer cell lines.

17957782

2008