CFTR, CF transmembrane conductance regulator, 1080

N. diseases: 476; N. variants: 673
Disease: Dry Eye Syndromes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013238
Disease: Dry Eye Syndromes
Dry Eye Syndromes 		0.030 Biomarker disease BEFREE Our results suggest the important role of CFTR in LG ductal secretion and in the maintenance of ocular surface integrity, suggesting that CFTR may be a promising target of novel therapeutic approaches in the treatment of dry eye. 29305607 2018
CUI: C0013238
Disease: Dry Eye Syndromes
Dry Eye Syndromes 		0.030 Biomarker disease BEFREE Pro-Secretory Activity and Pharmacology in Rabbits of an Aminophenyl-1,3,5-Triazine CFTR Activator for Dry Eye Disorders. 28873176 2017
CUI: C0013238
Disease: Dry Eye Syndromes
Dry Eye Syndromes 		0.030 GeneticVariation disease BEFREE Nanomolar-Potency Aminophenyl-1,3,5-triazine Activators of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel for Prosecretory Therapy of Dry Eye Diseases. 28099811 2017