CFTR, CF transmembrane conductance regulator, 1080

N. diseases: 476; N. variants: 673
Disease: Dryness of eye ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0314719
Disease: Dryness of eye
Dryness of eye 		0.030 Biomarker phenotype BEFREE Our results suggest the important role of CFTR in LG ductal secretion and in the maintenance of ocular surface integrity, suggesting that CFTR may be a promising target of novel therapeutic approaches in the treatment of dry eye. 29305607 2018
CUI: C0314719
Disease: Dryness of eye
Dryness of eye 		0.030 Biomarker phenotype BEFREE Pro-Secretory Activity and Pharmacology in Rabbits of an Aminophenyl-1,3,5-Triazine CFTR Activator for Dry Eye Disorders. 28873176 2017
CUI: C0314719
Disease: Dryness of eye
Dryness of eye 		0.030 GeneticVariation phenotype BEFREE Nanomolar-Potency Aminophenyl-1,3,5-triazine Activators of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel for Prosecretory Therapy of Dry Eye Diseases. 28099811 2017