PDE10A, phosphodiesterase 10A, 10846

N. diseases: 97; N. variants: 26
Disease: Dyskinetic syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013384
Disease: Dyskinetic syndrome
Dyskinetic syndrome 		0.120 AlteredExpression disease BEFREE The elevation of cyclic adenosine monophosphate/cyclic guanosine monophosphate levels by phosphodiesterase 10A inhibition may thus be targeted to reduce l-dopa-induced dyskinesia. 29508924 2018
CUI: C0013384
Disease: Dyskinetic syndrome
Dyskinetic syndrome 		0.120 GeneticVariation disease BEFREE Mutations in ADCY5 and PDE10A have been identified as important causes of childhood-onset dyskinesias and KMT2B mutations as one of the most frequent causes of complex dystonia in children. 29086067 2017
CUI: C0013384
Disease: Dyskinetic syndrome
Dyskinetic syndrome 		0.120 Biomarker disease HPO