HPSE, heparanase, 10855

N. diseases: 393; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis
0.030 GeneticVariation disease BEFREE There were significant differences in allele and genotype frequencies of HPA-1, -2, -3, and -5 among the three groups [CA(+), CA(-), and the control group] (P < 0.05), and significant differences in allele and genotype frequencies of HPA-1, -2, and -3 between groups CA(+) and CA(-) and the control group (P < 0.05). 25966234 2015
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis
0.030 AlteredExpression disease BEFREE Increased expression of heparanase in symptomatic carotid atherosclerosis. 23137827 2013
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis
0.030 Biomarker disease BEFREE Additionally, heparanase promotes thrombosis after vascular injury and contributes to a pro-coagulant state in human carotid atherosclerosis. 23499530 2013