Sarcoidosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Galectin-1 concentrations were significantly higher in BAL of IPF patients than in sarcoidosis and ILD-SSc patients and healthy controls.
|
31678459 |
2020 |
Sarcoidosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
The objective of this study was to identify DNA methylation and gene expression changes associated with chronic beryllium disease (CBD) and sarcoidosis in lung cells obtained by BAL.
|
30141971 |
2019 |
Sarcoidosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
BAL was performed in healthy volunteers and in patients with acute eosinophilic pneumonia (AEP), chronic eosinophilic pneumonia (CEP), and sarcoidosis.
|
30612125 |
2019 |
Sarcoidosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Sarcoidosis specimens consisted of two independent sets of formalin-fixed, paraffin-embedded lymph node biopsies, BAL, Kveim reagent, and fresh granulomatous spleen from a patient with sarcoidosis.
|
28846439 |
2018 |
Sarcoidosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Host-genotype analysis revealed an association of the rs2076530 (<i>BTNL2</i>) risk allele with a decrease in bacterial burden (p=0.002).Our results indicate Scadding type-dependent microbiota in sarcoidosis BAL samples.<i>Atopobium</i> spp. and <i>Fusobacterium</i> spp. were identified as sarcoidosis-associated bacteria, which may enable new insights into the pathogenesis and treatment of the disease.
|
29242257 |
2017 |
Sarcoidosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
The CCL8 concentrations in BAL fluid was significantly higher in 86 patients with IPF than those in 41 controls, and other interstitial lung diseases including non-specific interstitial pneumonia (n = 22), hypersensitivity pneumonitis (n = 20) and sarcoidosis (n = 19) (p < 0.005, respectively).
|
28057004 |
2017 |
Sarcoidosis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The serum levels of IP-10 were significantly increased only in patients with stages I and II sarcoidosis, while BAL fluid levels of ENA-78 were increased only in stage III sarcoidosis.
|
17052298 |
2006 |
Sarcoidosis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The gene expression in BAL fluid macrophages was higher than that in monocytes in patients with IPF (macrophages 1.23 +/- 0.48, vs monocytes 0.50 +/- 0.38, p < 0.05) and healthy subjects (nonsmokers: 1.66 +/- 1.17, vs 0.34 +/- 0.26, p < 0.05, smoker: 1.98 +/- 0.96, vs 0.34 +/- 0.48, p < 0.05, but sarcoidosis patients showed a higher expression of lipocortin I gene even in monocytes (2.62 +/- 1.87, vs 2.66 +/- 2.21).
|
9572000 |
1998 |
Sarcoidosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In an attempt to clear critical cytokines in the development and maintenance of sarcoid granuloma, we have measured the level of seven cytokine mRNA (TNF-alpha, IL-6, IL-8, TGF-beta, PDGF-B, IFN-gamma, and GM-CSF) in cells obtained by BAL from sarcoidosis patients and normal subjects.
|
8893383 |
1996 |
Sarcoidosis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
BAL in children: a controlled study of differential cytology and cytokine expression profiles by alveolar cells in pediatric sarcoidosis.
|
8769489 |
1996 |
Sarcoidosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
A significantly greater number of clones was detected in BAL compared with PBL in both groups (normal: 25.3 +/- 7.2 in PBL vs 62.8 +/- 5.2 in lung; sarcoid: 25.0 +/- 6.2 in PBL vs 90.0 +/- 6.6 in lung, mean value +/- SEM).
|
8120402 |
1994 |