|
Dengue Fever
|
0.100 |
Biomarker
|
disease |
BEFREE |
In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers.
|
28674411 |
2017 |
|
Dengue Fever
|
0.100 |
Biomarker
|
disease |
BEFREE |
The envelope protein (E protein) of dengue virus is responsible for a wide range of biological activities, including binding to host cell receptors and fusion to and entry into host cells.
|
29470620 |
2018 |
|
Dengue Fever
|
0.100 |
Biomarker
|
disease |
BEFREE |
Small molecules that target the dengue virus envelope protein, E, on the surface of the virion could act analogously to antibodies by engaging E extracellularly to block infection; however, a shortage of target-based assays suitable for screening and medicinal chemistry studies has limited efforts in this area.
|
30027735 |
2018 |
|
Dengue Fever
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In this study, two highly conserved regions of dengue envelope protein were identified and an scFv was constructed against it.
|
30629625 |
2019 |
|
Dengue Fever
|
0.100 |
Biomarker
|
disease |
BEFREE |
Zika (ZIKV) and dengue (DENV) virus infections elicit a robust but cross-reactive antibody response against the viral envelope protein, while antibody responses against non-structural proteins (NS) are more virus specific.
|
30902827 |
2019 |
|
Dengue Fever
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we focused on the Dengue viral envelope protein (E); computational analyses ranging from extensive Molecular Dynamics (MD) simulations and energy-decomposition-based prediction of potentially immunoreactive regions identified putative epitope sequences.
|
31003530 |
2019 |
|
Dengue Fever
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here, the consensus dengue virus envelope protein domain III fused to hydrophobin I of Trichoderma reesei was expressed in Pichia pastoris cultures and an in situ product removal by an ATPS using a non-ionic detergent, (Triton X-114) was performed.
|
30240632 |
2019 |
|
Dengue Fever
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here, we investigated four types of recombinant envelope protein domain III (DV-rED III) derived from four dengue virus (DENV) serotypes for diagnostic potential in detecting IgM in acute phase (mainly 2-3 days after onset of fever).
|
31311082 |
2019 |
|
Dengue Fever
|
0.100 |
Biomarker
|
disease |
BEFREE |
The virtual approach was based on generating different docking cycles of tetra, penta, hexa, and heptapeptide libraries by maximizing the discrimination between the amino acid motif in the ZIKV and dengue virus (DENV) envelope protein glycosylation site.
|
31533374 |
2019 |
|
Dengue Fever
|
0.100 |
Biomarker
|
disease |
BEFREE |
A star-shaped DNA architecture, carrying five molecular beacon-like motifs, was constructed to display ten dengue envelope protein domain III (ED3)-targeting aptamers into a two-dimensional pattern precisely matching the spatial arrangement of ED3 clusters on the dengue (DENV) viral surface.
|
31767992 |
2020 |
|
Dengue Fever
|
0.100 |
Biomarker
|
disease |
BEFREE |
Purified fusion proteins induced serotype-specific neutralizing antibodies without cross-reaction against other serotypes and arboviruses after mouse immunization. hydrophobin-fused domain III of dengue envelope protein could be a promising strategy for easy and low-cost production of components of a tetravalent sub-unit vaccine against dengue.
|
31828570 |
2020 |