Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Here, we show that Derlin-1 is overexpressed in breast cancer and exhibits oncogenic activities via interaction with UBE2C.
|
31670413 |
2020 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Interestingly, we found that there was a close relationship between the expression of BRCA1 and UBE2C in the MCF-7 and MDA-MB-231 breast cancer cell lines.
|
28881292 |
2017 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The positive expression rate of UBE2C in BRCA was 70.8% (148/209), and UBE2C expression in the adjacent breast tissue was negative.
|
29021715 |
2017 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our research in the current study demonstrated that up-regulation of UbcH10 was involved in breast cancer and its knockdown can inhibit the growth of cancer cells and increase the chemosensitivity of the dual drug resistant breast cancer cells to epirubicin and docetaxel, suggesting that UbcH10 may be a promising target for the therapy of breast cancer.
|
25739083 |
2015 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
In conclusion, the present study showed that miR-196a promoted cell proliferation by targeting UBE2C in breast cancer.
|
26062455 |
2015 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our findings suggest that deregulated AZGP1, PIP, S100A8 and UBE2C are critical for the aggressive breast cancer phenotype, which may be useful as novel therapeutic targets for drug development to complement established clinical variables.
|
24114735 |
2014 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
In this study, we evaluated whether UBE2C could be a tumor marker of early breast cancer with MC found on screening mammography.
|
24699941 |
2014 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of UBE2C was observed in all breast cancer cell lines tested using quantitative real time PCR.
|
24072565 |
2013 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
High UBE2C mRNA expression was found to be of adverse prognostic significance in high-risk breast cancer patients.
|
22056852 |
2012 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our results suggest a pathological correlation between UbcH10 and cell proliferation in breast cancer.
|
19038004 |
2009 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
We confirmed that UBE2C protein measured by IHC could be used as a prognostic marker in N+ breast cancer.
|
19513072 |
2009 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We have previously reported that UbcH10 overexpression is associated with aggressive thyroid, ovarian and breast carcinomas.
|
19438748 |
2009 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
CTD_human |
Prediction of metastatic relapse in node-positive breast cancer: establishment of a clinicogenomic model after FEC100 adjuvant regimen.
|
17659439 |
2008 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Consistently, the inhibition of breast carcinoma cell growth was achieved following the block of UbcH10 protein synthesis by RNA interference.
|
17933517 |
2007 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Combination of multiple mRNA markers (PTTG1, Survivin, UbcH10 and TK1) in the diagnosis of Taiwanese patients with breast cancer by membrane array.
|
17220641 |
2006 |