UBE2C, ubiquitin conjugating enzyme E2 C, 11065

N. diseases: 105; N. variants: 1
Disease: Carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 Biomarker disease BEFREE We believe that the miR-548e-5p-UBE2C-ZEB1/2 signal axis may be a suitable diagnostic marker and a potential target for lung cancer therapy. 31037155 2019
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 Biomarker disease BEFREE Activation of the oncogene UBE2C and repression of autophagy are concurrently underlying the initiation, progression, and metastasis of lung cancer and exploration of essential association of UBE2C with autophagy will confer more options in searching novel molecular therapeutic targets in lung cancer. 29904125 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 AlteredExpression disease BEFREE UBE2C is a proto-oncogene activated in lung cancer; however, its role in chemotherapeutic resistance is unclear. 30146342 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 AlteredExpression disease BEFREE Overexpression of UBE2C in lung cancer samples was correlated with advanced pathological stage. 25832867 2015
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 Biomarker disease BEFREE These results show UBE2C may represent a potential therapeutic target for lung cancer. 24815438 2014
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 AlteredExpression disease BEFREE The suppression of UbcH10 expression by RNAi resulted in a drastic reduction of proliferation and migration abilities of lung carcinoma cell lines. 23102841 2013