Carcinoma of lung
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
Adenocarcinoma of lung (disorder)
|
0.120 |
GeneticVariation
|
disease |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
Psoriasis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.
|
28537254 |
2017 |
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
Smoking
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
|
28443625 |
2017 |
Lean body mass
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.
|
30593698 |
2019 |
Diastolic blood pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
|
30224653 |
2018 |
Waist Circumference
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
New genetic loci link adipose and insulin biology to body fat distribution.
|
25673412 |
2015 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
|
28443625 |
2017 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
28448500 |
2017 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic studies of body mass index yield new insights for obesity biology.
|
25673413 |
2015 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.
|
30108127 |
2018 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
26426971 |
2015 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Physical Activity Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
28448500 |
2017 |
Non-Small Cell Lung Carcinoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Loss of heterozygosity (LOH) mapping of the HLJ1 locus was analyzed in 48 paired microdissected NSCLC tumors.All statistical tests were two-sided.
|
16788156 |
2006 |
Parkinsonism, Juvenile
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
DNAJC6 (DNA/HSP40 homolog subfamily C member 6) encodes auxilin, which is responsible for juvenile Parkinsonism with phenotypic variability.
|
25446072 |
2014 |
Carcinoma of lung
|
0.130 |
Biomarker
|
disease |
BEFREE |
Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1.
|
18794131 |
2008 |
Adenocarcinoma of lung (disorder)
|
0.120 |
Biomarker
|
disease |
BEFREE |
A serial deletion of the 1.2 kb at the 5'-flanking region of the human HLJ1 gene was subcloned into a vector containing reporter gene and transfected into human lung adenocarcinoma cell line CL1-0, followed by luciferase activity assay.
|
15782117 |
2005 |
Neoplasm Metastasis
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
HLJ1, a member of the heat shock protein 40 chaperone family, is a newly identified tumor suppressor that has been implicated in tumorigenesis and metastasis in non-small cell lung cancer.
|
20145123 |
2010 |
Neoplasm Metastasis
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
We conclude that HLJ1 is an endogenous Src inhibitor that can suppress cancer metastasis through complex interacting mechanisms.
|
27065329 |
2016 |
Neoplasm Metastasis
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
HLJ1 is a newly identified tumor and invasion suppressor that inhibits tumorigenesis and cancer metastasis.
|
22529897 |
2012 |
Neoplasm Metastasis
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
Together, we established, for the first time, a high-throughput targeted proteomics method for profiling quantitatively the human heat shock proteome and discovered DNAJB4 as a suppressor for melanoma metastasis.
|
29722524 |
2018 |