Disease: Impaired cognition ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.050 GeneticVariation disease BEFREE Higher baseline DELTA scores (stronger evidence of cognitive decline) predicted higher baseline CDR-SOB (ΔR2 = .318) and faster rates of CDR-SOB increase over time (ΔR2 = .209). 31822312 2019
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.050 Biomarker disease BEFREE These patterns were more apparent in at-risk ε4 carriers (Aβ42 in an allele dose-dependent manner) and appeared to be associated with future cognitive deficits as determined by CDR. 26147946 2015
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.050 Biomarker disease BEFREE Secondary outcomes included progression to CDR at least 0·5, symptomatic Alzheimer's disease (score of at least 0·5 for memory and at least one other domain and cognitive impairments deemed to be due to Alzheimer's disease), and mortality. 24012374 2013
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.050 GeneticVariation disease BEFREE Cox proportional hazards models demonstrated that an optimal panel of markers for predicting risk of developing cognitive impairment (CDR 0 to CDR>0 conversion) consisted of calbindin, Aβ42, and age. 21526197 2011
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.050 Biomarker disease BEFREE Cases were stratified into groups of 7-19 based on the degree of cognitive impairment (clinical dementia rating scale, CDR); neurofibrillary tangle distribution and severity (Braak staging) or density of cerebrocortical neuritic plaque (NP; grouping by NP density). 17845826 2009