Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.180 Biomarker disease BEFREE BTN2A1 may be a susceptibility gene for MI in Japanese individuals. 21211798 2011
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.030 Biomarker group BEFREE BTN2A1 may be a susceptibility gene for hypertension in Japanese individuals. 21525964 2011
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 Biomarker disease BEFREE BTN2A1 may be a susceptibility gene for Type 2 diabetes in Japanese individuals. 21672009 2011
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.020 Biomarker disease BEFREE BTN2A1 may be a susceptible gene for MetS in Japanese individuals. 21784758 2011
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias 		0.020 Biomarker group BEFREE BTN2A1 may thus be a susceptibility gene for dyslipidemia in community‑dwelling individuals. 24452779 2014
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.030 Biomarker group BEFREE BTN2A1 may thus be a susceptibility gene for hypertension. 25813534 2015
CUI: C0020557
Disease: Hypertriglyceridemia
Hypertriglyceridemia 		0.020 Biomarker phenotype BEFREE BTN2A1 may thus be a susceptibility gene for hypertriglyceridemia, hyper‑LDL cholesterolemia and CKD in Japanese individuals. 25813695 2015
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.030 Biomarker group BEFREE BTN2A1 may thus be a susceptibility gene for hypertriglyceridemia, hyper‑LDL cholesterolemia and CKD in Japanese individuals. 25813695 2015
CUI: C0021704
Disease: Intelligence
Intelligence 		0.100 GeneticVariation phenotype GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.020 GeneticVariation group BEFREE A multivariable logistic regression analysis adjusted for age, gender, body mass index, smoking status and the prevalence of diabetes mellitus revealed that rs6929846 of BTN2A1 was significantly (dominant model; P=2.4x10-4; odds ratio, 1.29) associated with dyslipidemia, with the minor T allele representing a risk for this condition. 24452779 2014
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.100 GeneticVariation disease GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.180 GeneticVariation disease GWASDB Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations. 21211798 2011
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.010 GeneticVariation disease BEFREE Considering that dyslipidemia is a significant risk factor for coronary heart disease, it was hypothesized that the association between rs6929846 of BTN2A1 and myocardial infarction may be attributable, at least in part, to its effect on the susceptibility to dyslipidemia. 24452779 2014
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.010 GeneticVariation disease BEFREE Considering that dyslipidemia is a significant risk factor for coronary heart disease, it was hypothesized that the association between rs6929846 of BTN2A1 and myocardial infarction may be attributable, at least in part, to its effect on the susceptibility to dyslipidemia. 24452779 2014
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.010 GeneticVariation disease BEFREE Considering that dyslipidemia is a significant risk factor for coronary heart disease, it was hypothesized that the association between rs6929846 of BTN2A1 and myocardial infarction may be attributable, at least in part, to its effect on the susceptibility to dyslipidemia. 24452779 2014
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.180 GeneticVariation disease BEFREE Considering that dyslipidemia is a significant risk factor for coronary heart disease, it was hypothesized that the association between rs6929846 of BTN2A1 and myocardial infarction may be attributable, at least in part, to its effect on the susceptibility to dyslipidemia. 24452779 2014
CUI: C0017168
Disease: Gastroesophageal reflux disease
Gastroesophageal reflux disease 		0.100 GeneticVariation disease GWASCAT Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases. 31527586 2019
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias 		0.020 GeneticVariation group BEFREE Genetic variants of APOA5 and BTN2A1 may synergistically affect the prevalence of dyslipidemia in East Asian populations and of MetS in Japanese individuals. 22576629 2012
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.020 GeneticVariation disease BEFREE Genetic variants of APOA5 and BTN2A1 may synergistically affect the prevalence of dyslipidemia in East Asian populations and of MetS in Japanese individuals. 22576629 2012
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.180 GeneticVariation disease BEFREE Given that diabetes mellitus is an important risk factor for myocardial infarction, the association of rs6929846 of BTN2A1 with myocardial infarction might be attributable, at least in part, to its effect on susceptibility to diabetes. 21672009 2011
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.020 GeneticVariation group BEFREE Given that diabetes mellitus is an important risk factor for myocardial infarction, the association of rs6929846 of BTN2A1 with myocardial infarction might be attributable, at least in part, to its effect on susceptibility to diabetes. 21672009 2011
CUI: C0011847
Disease: Diabetes
Diabetes 		0.010 GeneticVariation disease BEFREE Given that diabetes mellitus is an important risk factor for myocardial infarction, the association of rs6929846 of BTN2A1 with myocardial infarction might be attributable, at least in part, to its effect on susceptibility to diabetes. 21672009 2011
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.180 GeneticVariation disease BEFREE Given that hypertension is a major risk factor for myocardial infarction, the association of rs6929846 of BTN2A1 with myocardial infarction might be attributable, at least in part, to its effect on susceptibility to hypertension. 21525964 2011
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.180 GeneticVariation disease BEFREE Given that metabolic syndrome (MetS) is an important risk factor for myocardial infarction, the association of the rs6929846 of BTN2A1 with myocardial infarction might be attributable, at least in part, to its effect on susceptibility to MetS. 21784758 2011
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.100 GeneticVariation disease GWASDB GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. 24871463 2014