|
Myocardial Infarction
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
Considering that dyslipidemia is a significant risk factor for coronary heart disease, it was hypothesized that the association between rs6929846 of BTN2A1 and myocardial infarction may be attributable, at least in part, to its effect on the susceptibility to dyslipidemia.
|
24452779 |
2014 |
|
Myocardial Infarction
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
The results suggest that the relationship between rs6929846 of BTN2A1 or rs2569512 of ILF3 and MI is influenced by the serum concentrations of HDL and LDL cholesterol, respectively.
|
21468600 |
2011 |
|
Myocardial Infarction
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
Results suggested that the association of rs6929846 in BTN2A1 with MI was more apparent in low-risk individuals than in high-risk individuals, whereas the association of rs2569512 in ILF3 with MI was not influenced by the absence or presence of hypertension, DM or CKD.
|
21347509 |
2011 |
|
Myocardial Infarction
|
0.180 |
GeneticVariation
|
disease |
GWASDB |
Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations.
|
21211798 |
2011 |
|
Myocardial Infarction
|
0.180 |
Biomarker
|
disease |
BEFREE |
BTN2A1 may be a susceptibility gene for MI in Japanese individuals.
|
21211798 |
2011 |
|
Myocardial Infarction
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
We showed that the C→T polymorphism (rs6929846) of BTN2A1 and A→G polymorphism (rs2569512) of ILF3 were significantly associated with myocardial infarction in Japanese individuals by a genome-wide association study.
|
21557786 |
2011 |
|
Myocardial Infarction
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
Given that hypertension is a major risk factor for myocardial infarction, the association of rs6929846 of BTN2A1 with myocardial infarction might be attributable, at least in part, to its effect on susceptibility to hypertension.
|
21525964 |
2011 |
|
Myocardial Infarction
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
Given that diabetes mellitus is an important risk factor for myocardial infarction, the association of rs6929846 of BTN2A1 with myocardial infarction might be attributable, at least in part, to its effect on susceptibility to diabetes.
|
21672009 |
2011 |
|
Myocardial Infarction
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
Given that metabolic syndrome (MetS) is an important risk factor for myocardial infarction, the association of the rs6929846 of BTN2A1 with myocardial infarction might be attributable, at least in part, to its effect on susceptibility to MetS.
|
21784758 |
2011 |
|
Gastroesophageal reflux disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases.
|
31527586 |
2019 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.
|
29326435 |
2019 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
|
29844566 |
2018 |
|
Major Depressive Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.
|
29942085 |
2018 |
|
Child Development Disorders, Pervasive
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Breast Carcinoma
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Association analysis identifies 65 new breast cancer risk loci.
|
29059683 |
2017 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
Lupus Erythematosus, Systemic
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
|
24871463 |
2014 |
|
Hypertensive disease
|
0.030 |
Biomarker
|
group |
BEFREE |
BTN2A1 may thus be a susceptibility gene for hypertension.
|
25813534 |
2015 |
|
Chronic Kidney Diseases
|
0.030 |
Biomarker
|
group |
BEFREE |
BTN2A1 may thus be a susceptibility gene for hypertriglyceridemia, hyper‑LDL cholesterolemia and CKD in Japanese individuals.
|
25813695 |
2015 |
|
Hypertensive disease
|
0.030 |
Biomarker
|
group |
BEFREE |
BTN2A1 may be a susceptibility gene for hypertension in Japanese individuals.
|
21525964 |
2011 |
|
Hypertensive disease
|
0.030 |
GeneticVariation
|
group |
BEFREE |
Results suggested that the association of rs6929846 in BTN2A1 with MI was more apparent in low-risk individuals than in high-risk individuals, whereas the association of rs2569512 in ILF3 with MI was not influenced by the absence or presence of hypertension, DM or CKD.
|
21347509 |
2011 |
|
Chronic Kidney Diseases
|
0.030 |
Biomarker
|
group |
BEFREE |
Our results suggest that BTN2A1 may be a susceptibility gene for CKD in Japanese individuals.
|
21557786 |
2011 |
|
Chronic Kidney Diseases
|
0.030 |
GeneticVariation
|
group |
BEFREE |
Multivariable logistic regression analyses with adjustment for covariates revealed that rs6929846 of BTN2A1 was significantly associated with MI in individuals with (P=0.0001; odds ratio, 1.49) or without (P=1.6x10-7; odds ratio, 2.32) hypertension; in individuals with (P=0.0002; odds ratio, 1.65) or without (P=8.1x10-7; odds ratio, 1.76) DM; and in individuals without CKD (P=6.0x10-11; odds ratio, 2.03), but not in those with CKD.
|
21347509 |
2011 |
|
Hypertriglyceridemia
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
BTN2A1 may thus be a susceptibility gene for hypertriglyceridemia, hyper‑LDL cholesterolemia and CKD in Japanese individuals.
|
25813695 |
2015 |