CHI3L1, chitinase 3 like 1, 1116

N. diseases: 420; N. variants: 9
Disease: Secondary Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm 		0.040 Biomarker group BEFREE We investigated the metastases in lung tissues of C57BL/6 mice injected with B16F10 melanoma following treatment with Ad-shChi3L1. 30214629 2018
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm 		0.040 Biomarker group BEFREE CHI3L1 is associated with tumor metastasis and might be a prognostic biomarker for papillary thyroid carcinoma. 28009325 2017
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm 		0.040 AlteredExpression group BEFREE Activation of IL-13Rα2 by CHI3L1 triggered the activation of the mitogen-activated protein kinase signaling pathway, leading to the upregulated expression of matrix metalloproteinase genes, which promoted tumor metastasis. 28143526 2017
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm 		0.040 Biomarker group BEFREE Both our case reports were adult males who developed extra-CNS, YKL-40-positive metastases at lymph nodes, lung and subcutaneous sites, after 86 and 24 months from initial diagnosis of GBM. 26212701 2016