CHIT1, chitinase 1, 1118

N. diseases: 142; N. variants: 8
Disease: Allergic asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.030 Biomarker disease BEFREE This study was undertaken to investigate the potential contribution of NOD2 signaling, proinflammatory cytokines, chitotriosidase (CHIT1) activity, oxidative stress and DNA damage to atopic asthma pathogenesis, as well as to explore their possible role as surrogate noninvasive biomarkers for monitoring asthma severity. 29572197 2018
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.030 Biomarker disease BEFREE We hypothesized that Chit1 plays a significant role in the pathogenesis of allergic asthma. 29420850 2018
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.030 Biomarker disease BEFREE CCL18, chitotriosidase (CHIT1) and YKL-40 are readily detectable in the lungs and contribute to remodelling in other fibrotic diseases, but their involvement in allergic asthma is unclear. 23331560 2013