NISCH, nischarin, 11188

N. diseases: 49; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE Furthermore, we observed significantly increased tumor growth and metastasis in Nischarin mutant animals. 31525254 2020
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE Accordingly, NISCH knockdown xenografts exhibited increased peritoneal/pelvic metastases that were not present in counterparts treated with PF-562271. 25724667 2015
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 AlteredExpression phenotype BEFREE Nischarin expression may therefore be used as a marker to predict the invasiveness and metastasis of PBC. 25695373 2015
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 AlteredExpression phenotype BEFREE MDA-MB-231 cells in which nischarin was overexpressed had statistically significantly reduced tumor growth and metastasis compared with parental MDA-MB-231 cells (mean volume at day 40, control vs nischarin-expressing tumors, 1977 vs 42.27 mm(3), difference = 1935 mm(3), 95% CI = 395 to 3475 mm(3), P = .025). 21917605 2011