WIF1, WNT inhibitory factor 1, 11197

N. diseases: 171; N. variants: 1
Disease: Childhood Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 AlteredExpression disease BEFREE The WNT inhibitory factor 1 (WIF1), a secreted inhibitor of WNTs, is systematically downregulated in glioblastoma and acts as strong tumor suppressor. 25772239 2016
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 PosttranslationalModification disease BEFREE Levels of WIF1 promoter methylation, mRNA expression, and protein expression in a glioblastoma cell line were compared before and after demethylation treatment. 23328978 2013
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 Biomarker disease BEFREE Wnt inhibitory factor-1 regulates glioblastoma cell cycle and proliferation. 22901505 2012
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 AlteredExpression disease BEFREE Interestingly, WIF1 overexpression in glioblastoma cells induced a senescence-like phenotype that was dose dependent. 21642372 2011